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SIL-FREE MEDICINE

PACKAGED MEDICINE INFORMATION

This leaflet answers some common questions about LACT-FREE MEDICINE.

The information provided should not be used as a substitute for your medical advice.

Ask your doctor or pharmacist to review this leaflet.

You may refer to any of the information this leaflet contains.

To learn more about LACT-FREE MEDICINE, see the contents on the booklet.

You may also consult a doctor or pharmacist.

What is LACT-FREE MEDICINE?

LACT-FREE (lactose-free non-steroidal anti-inflammatory drugs) is used in adults and children to treat symptoms of pain, inflammation, swelling, and stiffness and relieve symptoms of an inflamed pain in the knee. It is also used to treat pain from the following:

• Joint pain and swelling (inflammation of the joints) in adults and children

• Pain from inflammation of the ligaments, muscles and tendons

• Joint injury

The recommended dose is one 2.5mg tablet taken once a day for 7 days. If you are taking other anti-inflammatory medicines, you may take it up to 4 weeks before pain begins.

The effects of LACT-FREE medicines can last up to 7 days.

If this does not help, you may not need to take it.

Your doctor may give you a reduced dose.

LACT-FREE tablets contain the following inactive ingredients: lactose monohydrate, magnesium stearate, sodium lauryl sulfate, titanium dioxide, and lactose.

WHAT IS LACT-FREE MEDICINE?

The active ingredient in LACT-FREE tablets is lactose-free.

The usual dose of LACT-FREE tablets is one 2.5mg tablet taken once a day for 7 days.

LACT-FREE tablets contain the following inactive ingredients: lactose monohydrate, magnesium stearate, titanium dioxide, and lactose.

WHAT YOU NEED BEFORE Taking LACT-FREE tablets?

Do not take LACT-FREE tablets if you are allergic to lactose (or any of the other ingredients listed at the end of this leaflet).

Lactose can pass through broken or non-YE absorbable clothing and mucus. If you are not sure you can take LACT-FREE tablets, talk to your doctor or pharmacist before taking this medicine.

Some medicines may make LACT-FREE tablets difficult to swallow or take for a number of reasons, including:

• It may irritate the stomach or intestines

• You may be sick (such as a bad asthma attack)

• Lactose-containing products do not protect you

• The medicine contains lactose.

Talk to your doctor before taking this medicine if:

• You have severe kidney problems

• You are over 65 years of age

• You have an irregular heartbeat

• You have bleeding or bruising

Lactose-containing medicines may cause diarrhea or stomach bleeding. If you or your doctor notice these symptoms, tell your doctor as soon as possible.

Other side effects of LACT-FREE tablets may include stomach pain, feeling sick (stomachache), diarrhoea and rash. Lactose-containing medicines, or LACT-FREE tablets, may also help to reduce the effects of certain blood-sugar medicines, such as dihydroergotamine, loratidine, orexinin, sumatriptan, and so on.

Lactose-containing medicines may make it more difficult to swallow LACT-FREE tablets. To see if this is an issue, ask a pharmacist.

Background:The aim of this study was to examine the effect of co-administration of metronidazole (a drug with a limited spectrum) and lansoprazole (a drug with a broader spectrum of activity) on the effects of tetracycline on human colonic epithelial cell (CEC).

Methods:CEC were isolated from healthy human colonic mucosa and cultured in alactose-freeco-treatment group. All cultures were incubated in the presence or absence of metronidazole (50 mg/ml) for 24 h and then examined for expression of cell adhesion molecule (CAM) by immunohistochemistry. Colonic epithelial cells (CEC) were fixed and immunohistochemically stained with CD68 and p-MMP.

Results:CEC cultured in the co-treatment group were more sensitive to metronidazole than cultured in the control group (p < 0.05). The mean time of metronidazole treatment was 12.5 h in both groups. CEC cultured in the co-treatment group expressed higher levels of expression of cell adhesion molecule (CAM) compared to the control group (p < 0.05).

Conclusions:Co-administration of metronidazole and lansoprazole significantly increased the expression of the cell adhesion molecule in CEC. This was associated with a decrease in the time to the final staining of CD68 and p-MMP.

CLAVULANIDAZole (clonidine hydrochloride) is an antifungal drug which inhibits the activity of fungal enzymes.Nature1309(23), 438–44 (19) Jan. 2013,2(9):e22. doi:10.1002/ncn.2014.25

Acyclovir (acyclovir hydrochloride), the active compound in the class of fluoroquinolones, is a potent inhibitor of the DNA-dependent DNA gyrase (DNA gyrase) and the topoisomerase IV, which are DNA-binding enzymes involved in the metabolism of DNA. Its inhibitory activity is due to its high affinity for DNA gyrase and topoisomerase IV and is responsible for the transcriptional activation of the gene. Thus, this is a first-line treatment for fungal infections. However, there are many potential side effects associated with the use of this drug, including gastrointestinal disturbances (gastritis, nausea, vomiting, diarrhea, nausea, and abdominal pain), blood disorders (thrombocytopenia, agranulocytosis), renal toxicity (nausea, vomiting, hypertension, heart failure, angioneurotic lesions), and hypersensitivity reactions (all of which can occur with concurrent use of systemic corticosteroids and immunosuppressive therapy).

Introduction

The development of a class of fluoroquinolones known as the fluoroquinolones is a new area of research which has revolutionized the treatment of infectious diseases. Since the 1970s, fluoroquinolones have been used for the treatment of various infections. The most common type of infection involved is respiratory tract infections caused by Mycoplasma hominis, Chlamydia trachomatis, or the human chlamydia organism (HPV). The use of fluoroquinolones has been approved for this indication by the United States Food and Drug Administration (US FDA) for the treatment of infections caused by Mycoplasma genitalium, Mycoplasma smegmatis, or M. smegmatis (; ; ). However, the use of these drugs for the treatment of Mycoplasma infections is associated with a number of undesirable side effects including nausea, vomiting, diarrhea, and abdominal pain. This paper aims to review the current literature on the use of fluoroquinolones and its effects on the clinical use of this drug, as well as the potential side effects associated with the use of fluoroquinolones.

Table 1.

Acyclovir

The literature search was done using the MEDLINE (1966-December 1, 2010) and the EMBASE (1988-December 1, 2006) databases.

The Science Behind Actos: A New Drug and Its Role in Diabetes Care

Actos (pioglitazone) has been a staple in diabetes care for over 15 years. With its unique combination of insulin, a thiazolidinedione, and glucagon-like peptide-1 receptor agonist (GLP-1R-1), it has become a go-to medication for managing diabetes effectively. Its primary mechanism involves activating the insulin receptor, which plays a pivotal role in regulating glucose levels in the bloodstream. This dual action has made Actos a cornerstone of diabetes care, offering hope to millions seeking effective management of diabetes.

While Actos has proven efficacy in many cases, it is important to be aware of the potential side effects and contraindications associated with its use. In this comprehensive article, we explore the science behind Actos, how it works, potential side effects, and how effective it is for managing diabetes.

Understanding Actos and Its Side Effects

Actos, also known by its generic name pioglitazone, is an injectable medication used to treat type 2 diabetes. Unlike its more immediate-acting counterpart, Actos requires a specialized healthcare provider's supervision to manage the side effects of the medication. Patients may experience mild gastrointestinal upset, headache, or dizziness while taking Actos.

Actos side effects range from mild to severe, and include:

  • Insomnia
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Increased blood sugar levels
  • Oily spotting or flatulence
  • Headaches
  • Muscle pain
  • Dizziness

In addition to these common side effects, Actos may cause more serious reactions, including:

  • Hives
  • Facial swelling
  • Blurred vision
  • Sudden hearing decrease or ringing in the ears
  • Seizures
  • Sudden numbness or weakness in the arms and legs

In rare cases, Actos has also been linked to serious liver damage, which can lead to a life-threatening situation. Symptoms include nausea, vomiting, abdominal pain, and irregular menstrual cycles.

Uses of Actos for Diabetes Management

The journey of managing diabetes involves a comprehensive approach to care. It involves a combination of lifestyle changes, support from your healthcare provider, and adjustments to your diet and regular exercise plan to help maintain the health of your body. The goal of diabetes management is to ensure you have enough insulin to manage your blood sugar levels effectively.

To help you navigate the complexities of diabetes management, we have listed the following resources and services available to help you manage your diabetes effectively:

  • GLP-1R-1 Medications- Actos is a medication that helps regulate blood glucose levels in the body. It is often prescribed to treat type 2 diabetes when used as needed, but it does not impact insulin sensitivity or the absorption of glucose from the bloodstream. By stimulating the release of insulin, Actos reduces the need for sugar, thereby helping to maintain blood glucose levels in the body. Additionally, Actos can be used in conjunction with other diabetes treatments like Metformin or MetforminRx, which are often recommended for type 2 diabetes patients. It may also be prescribed for other medical conditions, such as high blood pressure or hypertension.
  • Beta-blockers- Actos has been approved for the treatment of type 2 diabetes by the FDA since the late 1980s. It has been found to be effective in reducing the risk of sudden weight gain and reducing the rate of blood sugar levels. It is also used to treat high blood pressure, heart failure, and hypertension, but it has not been studied as extensively as Actos for this purpose. It is also used to treat type 2 diabetes as an adjunct to other medications such as insulin.
  • GLP-1R-1 Therapy- Metformin is a medication that is sometimes used to treat Type 2 diabetes, but it does not have a direct impact on the absorption of glucose from the bloodstream. By reducing the amount of insulin released into the bloodstream, Metformin improves the absorption of glucose from the bloodstream, thereby helping to control blood sugar levels. Metformin is a type of drug commonly prescribed for Type 2 diabetes by patients. MetforminRx, also known as metformin, is an FDA-approved medication that has been used to treat type 2 diabetes for decades.

Eli Lilly and Company has filed a new patent for the generic version of its diabetes drug, Actos, which is indicated for the treatment of Type 2 diabetes. The patent is expected to expire in the spring of 2014. The generic version of Actos, Lilly’s second-biggest diabetes drug, is expected to be available in the U. S. in the same amount of time and with the same safety as the branded version, according to a recent report from Eli Lilly’s.

Actos, which is marketed as the “Generic” version, has a much lower cost than the brand-name version. Actos costs about $7.08 per pill, compared with about $2.75 per pill for generic diabetes drugs like Humalog and Humulin. Lilly also sells generic versions of the drug, which are available at the lower end of the range.

A generic drug is a drug that has the same active ingredients as the brand-name drug. For example, it’s the same chemical that makes the brand-name version of the diabetes drug, Actos.

The Lilly filing for the patent for the generic version will probably make a big difference to what people think of Actos. “This is a generic drug,” Lilly said in an interview. “It will help the brand-name version of Actos, the original brand-name version, and the generic version, the brand-name version.”

The Lilly filing also will make it possible for Lilly to apply for a patent on the generic version of Actos. “This is a generic drug that has been in the marketplace for a long time,” Lilly spokeswoman Lyndsay M. Johnson said. “This is a generic drug, and the patent will apply to it.”

Actos is Lilly’s second-biggest brand-name diabetes drug. The drug’s patent has since expired. But there are no generic drugs available. Generic drugs are generally cheaper than their brand-name counterparts, said Robert J. Geddes, chairman of pharmaceuticals at Eli Lilly, which has its headquarters in Indianapolis.

The generic version of Actos costs about $7.08 per pill. It’s the same chemical that makes the brand-name version of the diabetes drug, Actos.

The Lilly filing for the generic version will probably make a big difference to what people think of Actos. “This is a generic drug,” Lilly spokeswoman Johnson said. “This will help the brand-name version of Actos, the original brand-name version, and the generic version, the brand-name version.”

“This is a generic drug,” Johnson said.

“This will help the brand-name version of Actos, the original brand-name version, and the generic version, the brand-name version.